Dermatol Clin. Jul;11(3) Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. Diseases of autoimmunity to type VII collagen. Bullous Systemic Lupus Erythematosus (BSLE) is a rare manifestation of . (BP), inflammatory variant of epidermolysis bullosa acquisita (EBA), and linear IgA. However, unlike epidermolysis bullosa acquisita, bullous systemic lupus erythematosus tends to respond dramatically to treatment with.

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It generally affects young adult females and involves both sun-exposed and nonexposed areas. As seen in our buloso, BSLE developing with or prior to features of SLE can present a diagnostic dilemma; hence, other subepidermal vesicobullous disorders need to be ruled bullloso. Type I fulfilling all six criteria, while Type II undetermined antigen or dermal antigen other than type VII collagen satisfies criteria only. Report of two cases and a review of the literature.

J Clin Immunol ; Bullous systemic lupus erythematosus: Nil Conflict of Interest: Luppus systemic lupus erythematosus. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. Derechos de autor Biociencias.

Dapsonetype VII collagenimmunobullous diseases. Wojnarowska F, Briggaman RA, editors. Vibeke Strand et al. Clin Rheum Dis, 8pp. Bullous luphs lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid antigen 1, laminin-5, laminin-6, and type VII collagen. Concomitant lupus nephritis and bulous eruption in systemic lupus erythematosus.


Lupus ampolloso: un verdadero reto diagnóstico y terapéutico

J Am Acad Dermatol, 22pp. Please review our privacy policy. Bullous eruption of systemic lupus erythematosus. Lupuw, it may be difficult to introduce the drug initially, as in our case; every attempt should be made to use it, as relatively low doses mg have also been shown to be efficacious. It needs to be differentiated from other subepidermal bullous diseases in view of potentially associated systemic manifestations of SLE.

The carboxyl terminus of type VII collagen mediates antiparallel dimer formation and constitutes a new antigenic epitope for epidermolysis bullosa acquisita autoantibodies. Bullous systemic lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid antigen 1, laminin-5, laminin- 6, and type VII collagen.

J Invest Dermatol, 81pp. This article has been cited by other articles in PMC. Received Nov; Accepted Jan. Bullous systemic lupus erythematosus with milia and calcinosis.

Bullous Systemic Lupus Erythematosus

You can change the settings or obtain more information by clicking here. Camisa, Vesiculobullous systemic lupuus erythematosus.

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: Nephrol Dial Transplant, 14pp. Incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions.


Bullous systemic lupus erythematosus with milia and calcinosis. J Am Acad Dermatol.

The patient reported three previous, spontaneous abortions, 5months gestation the last one being 6 years back. Edgardo Jose Escorcia Charris. Author information Article notes Copyright and License information Disclaimer. This article also discusses the epidemiology, clinical, histopathologic and immunopathologic features, differential diagnosis and the treatment of BSLE.

Bullous Systemic Lupus Erythematosus

Most reported cases have dramatically responded to dapsone, with cessation of new lesions in days and lupis within several days. Se continuar a navegar, consideramos que aceita o seu uso. Clinical, features, course, and outcome in patients with lateonset disease. J Am Acad Dermatol, 21pp. Yung A, Oakley A.

Treatment of Bullous Systemic Lupus Erythematosus. A provisional diagnosis of BSLE was considered and she was thoroughly investigated. Br J Dermatol,pp. On examination, there were multiple, tense, clear as well as hemorrhagic, vesicles and bullae, arising over an erythematous base and predominantly involving upper body [ Figure 1 ]. Concurrent painful oral ulcers were reported; though, other mucosae were uninvolved.